Scientific Reports of the National University of Life and Environmental Sciences of Ukraine

Features of the immunogenetic structure of pigs of domestic breeds, suitable for xenotransplantation

T. Ryk
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Abstract

The comparative assessment of the immunogenetic status of pigs of the Ukrainian meat-type and Myrgorod pigs has been carried out. The specificity of immunogenic profiles has been evaluated, depending on the history of creation and the direction of the productivity of animals. It has been found out that 24 specimens of Myrhorod pigs and 13 specimens of the Ukrainian meat-type pigs have the presence of genotypes А-/- and Еbdgkmp/ bdgkmp which determine the suitability of animals for xenotransplantation. The Ukrainian meat-type pigs and Myrgorod pigs had the largest differences in the distribution of alleles by B, E, F, K, L blood group systems with the presence of the Ladhjk marker allele in the specimens of Myrgorod pigs. (p <0.05). The possibility of occurrence of reproductive and resistance disorders of pigs in the selection by blood groups genotypes modeled for xenotransplantation and the search for ways to their selection overcoming are discussed

Keywords

erythrocyteantigen, polymorphism, allele, pigs, immunogenetic profile, xenotransplantation

Suggested citation
Ryk, T. (2022). Features of the immunogenetic structure of pigs of domestic breeds, suitable for xenotransplantation. Scientific Reports of the National University of Life and Environmental Sciences of Ukraine, 18(1). https://doi.org/10.31548/dopovidi2022.01.002
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