Scientific Reports of the National University of Life and Environmental Sciences of Ukraine

New possibilities of bioregulatory approach in therapy of cow mastitis

D. Tarnavskiy, S. Girin, M. Guliy, O. Gorenkova, T. Tkachenko, V. Tkachenko
Download article
Abstract

Food security includes not only the mater of provision of basic foodstuffs to the population, but also the guarantee of their quality and safety for the consumer. These criteria are, especially, important for milk as the main food products. The pathological processes, which are developed in the breast, have negative effect on the quality of milk, and the medical products that are used in their treatment, may affect on the safety of this product. In the article are represented the results of experimental research with the studying of an effectiveness of the bioregulatory approach in the treatment of catarrhal mastitis in cows with the use of medical products, which contain ultra-low doses of biologically active substances. According to the results of the research was found, that the most effective is a combined scheme of treatment of mastitis, which includes the systemic antibiotic Ceftionel, intramuscular injection of Traumeel, intracisternal therapy of Lachesis compositum and local therapy of Traumeel( gel). These products haven’t a withdrawal period towards regarding milk. On the 6th day of treatment of catarrhal mastitis recovered 100% of cows in this group, and an average duration of treatment was 5.1 days. In the group of cows, which were treated with Ceftionel-50, the nonsteroidal anti-inflammatory product Ketoprosen, the syringe-tubes for intracisternal administration Mastamox and udder treatment with Sanofit ointment, only 40% of animals recovered on 6th day, and the mean duration of treatment for catarrhal mastitis was 7.8 days. Animals, which were treated, exclusively, with bioregulatory products for the treatment of catarrhal mastitis, an effectiveness of treatment was 57% on the 6th day, and an average period of complete recovery was 5.7 days. So, the bioregulatory therapy in combination with the antibiotic Ceftionel provides synergistic action and high efficiency with correcting many pathogenetic mechanisms of the inflammatory response, as well as a high safety level of therapeutic measures

Keywords

catarrhal mastitis, bioregulatory products

Suggested citation
Tarnavskiy, D., Girin, S., Guliy, M., Gorenkova, O., Tkachenko, T., & Tkachenko, V. (2022). New possibilities of bioregulatory approach in therapy of cow mastitis. Scientific Reports of the National University of Life and Environmental Sciences of Ukraine, 18(1). https://doi.org/10.31548/dopovidi2022.01.014
References
  1. Bala, S.S. (2010). Biological properties of microflora isolated from milk of cows with clinical and subclinical forms of mastitis. News of Orenburg State Agrarian University, 4(28-1), 287-289.
  2. Valchuk, O., & Stoliuk, V. (2010). Mastitis of cows caused by pathogens of bacterial nature. Propozytsiia, 9, 118-121.
  3. Karpenko, A.V. (2017). Product quality management as a key factor in ensuring the competitiveness of dairy products caused by pathogens of bacterial nature. Economics and Enterprise Management, 20, 345-350.
  4. Kushnir, I.M. (2017). Problems of breast diseases and prospects for the development of new antimastitis drugs. Scientific Bulletin of Lviv National University of Veterinary Medicine and Biotechnology Named After S.Z. Gzhytsky, 19(82), 93-96.
  5. Luchko, I.T. (2019). Inflammation of the mammary gland in cows (etiology, pathogenesis, diagnosis, treatment and prevention). GGAU, 184.
  6. Maslov, M. (2002). Treatment of mastitis without stress. Livestock for Everyone, 2, 40-45.
  7. Murska, S.D. (2016). Modern scientific approaches to ensuring the quality of milk and the development of safe drugs without antibiotics for the treatment of cows with mastitis. Scientific Bulletin of Lviv National University of Veterinary Medicine and Biotechnology Named After S.Z. Gzhytsky, 18(1), 205-220.
  8. Salina, A., Timenetsky, J., Barbosa, M., Azevedo, C., & Langoni, H. (2020). Microbiological and molecular detection of Mycoplasma bovis in milk samples from bovine clinical mastitis. Pesquisa Veterinária Brasileira, 40(2), 82-87.