The relevance of the presented scientific results is caused by global ecotoxicological loads that is grown in agroecosystems. It has threat of toxicity increase in the trophic chain plant-animal-human, which is the characteristic to forage agroecosystems. The results are presented in the article were obtained in a short-term field experiment during 2016-2018 by the Institute of Agriculture of Polissia National Academy of Agrarian Sciences of Ukraine. The experiment was realisedon Luvisolic Ferro-HumicPodzol soilsin the Korosten agricultural soil’s region of Central Polesia. The experiment was carried out in a 3-fieldcrop rotation of Narrow-leaved Lupine - Winter wheat – Corn for green mass. The last one were grown for green mass. The effectiveness of IV-th generation herbicides and their tank mixtures with I-stgeneration herbicides were studied. The herbicides application gave additional yields of Narrow-leaved lupine - up to 0,28…0,60 t / ha (+ 25,2 % ... + 54,1 % in addition to control); Winter wheat - up to 0,39 -0,77 t / ha (+ 17,5 % ... + 32,5 % to control), Corn for green mass - up to 17,334,0 t / ha (+ 156 % ... + 306 % to control). The maximum effect for prevention of crop losses and reduction of weed levels was exerted by the protection system based on tank mixtures of herbicides of I-st and IV-th generations: Narrow-leaved lupine (Prado + Bazagran) - Winter wheat (Granstar Pro 75 + Prima) - Corn for green mass (Titus + Prima). But it led to an increase ecotoxicological pollution risk to agroecosystem in 17 times compare to the system based on IV-th herbicides generation (Prado, Granstar and Titus), although it supported the risk of ecotoxicological loads in theforage agroecosystem at level of “low hazard”. The application of I-st generation herbicides (Bazagran, Prima) is impractical, due to increased risk of ecotoxicological load by 12.5… 42.3 times compared to IV-th generation herbicides (Prado, Granstar Pro, Titus). Under the conditions of a large number of herbicides on the market, the producer requires information on the compensation of the ecotoxicological load in the agroecosystem with yield growth (reduction of weediness) to justify the economic and environmental feasibility of the drug. Therefore, an additional indicator was proposed - the ecological risk justification coefficient (Cerj), which indicates what share of the additional crop is compensated by the increase in possible soil pollution with pesticides. According to the results of the AETI and Cerj assessment, it was proved that, in general, for rotation of the studied fodder crop rotation, the least environmentally risky and justified yield increasable is such a system of plant protection against weeds based on IV-th herbicides generation: narrow-leaved lupine (Prado) - winter wheat (Granstar Pro ) - corn for green mass (Titus), which provides compensation for the increase in possible soil contamination by germination of crop yields on average for crop rotation at the level of 209 tons of feed units per conventional 1 kilogram of possible herbicides soil contamination
herbicides; fodder crop rotation; ecotoxicological load; environmental risk